Five defendants, including three siblings, have pled not guilty to charges connected to a drug bust in Lagunitas last month. The suspects—Mark Woodard, 58; Isaiah Makonen, 28; Forever Makonen, 25; Starlight Makonen, 23; and Sarah Gilmore, 22—face several counts, including for manufacturing illegal drugs, conspiring to commit a crime, obstructing arrest, destroying evidence, and possessing a controlled substance for sale. The possession for sale charge, initially filed by the Marin County District Attorney’s Office as a single count, has been updated to three counts corresponding to the various drugs allegedly found in the defendants’ possession: DMT, LSD, and psilocybin mushrooms. In Marin, this felony could carry a sentence of four years and court fines up to $20,000. On Aug. 5, sheriff’s deputies uncovered the alleged psychedelic drug operation in the neighborhood once called home by Janis Joplin and Big Brother and the Holding Company. Deputies recovered almost 24 pounds of DMT powder and 2.29 pounds of psilocybin mushrooms. (DMT can be produced synthetically in a lab or extracted from certain plants. When ingested, both DMT and psilocybin can produce hallucinations and a sense of euphoria.) A statement filed by Joseph Hart, a deputy with the sheriff’s office, offered further details from the scene that unfolded around the arrests. Mr. Hart described hearing and witnessing the suspects flushing a powder substance down toilets and showers and seeing Mr. Woodard drop a bag that contained a white powdered substance. “Inside the residence, molds for gel tabs, scales, cooking equipment, as well as stainless steel tables were located,” he wrote, noting that “multiple notes were found with orders as well as USPS receipts and new packaging.” In response to a court order requiring the defendants to wear GPS monitors and prohibiting them from traveling out of state, Ms. Gilmore’s attorney asked Marin County Superior Court Judge Kevin Murphy to ease those restrictions, noting that his client is enrolled at an out-of-state university. On Sept. 4, the judge ordered the removal of the monitors from all defendants. The next hearing takes place on Oct. 28.