Donald Glaser, a Nobel Prize-winning scientist whose astonishing invention of the bubble chamber contributed to the postwar foundation of particle physics and whose subsequent forays into other fields presaged the viability of biotechnology, died Feb. 28 in Berkeley. The part-time Inverness resident was 86.

While physics was once the domain of theorists working alone with mathematical equations and small groups of experimentalists doing tabletop experiments, during the 1930s and 40s (before and after the World…